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Microsoft MVP - Office 365
I think you need FOPE Standalone to solve that problem.
I totally agree, it's a real pain to setup several IIS SMTP relay for differrent services/systems/devices
Please see the link below.
Some messages are rejected when you try to use Exchange Online servers as an SMTP relay for on-premises business applications and network hardware devices:
For a full, cloud-based SMTP relay experience, purchase a FOPE stand-alone subscription to enable SMTP relay through Microsoft Online Services.
Also see the link below about FOPE connectors:
Hope this help.
Thanks for the Info Jesper. Need to engage Microsoft to implement a more user friendly way to do SMTP relay with Exchange ONline.
Did anyone ever figure this out, I have some SMTP working for a few scanners, and software, but for sending to external addresses not so much.
Did you try the suggestion above?
If the issue still exists, I would suggest you post a new thread about the detailed information of the issue you encountered and the steps you have done to resolve it, this is so we could focus on your questions and provides more specific solutions for you.